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In this manner, although frequent discharge of stool is not prevented, dehydration is successfully corrected. Opioids. Activation of opioid receptors in the enteric nerve plexus results in inhibition of propulsive motor activity and enhancement of segmentation activity. This antidiarrheal effect was formerly induced by application of opium tincture (paregoric) containing morphine.
stimulation of aldosterone secretion, leading to increased renal reabsorption of NaCl and water, hence an increased blood volume; (3) a central increase in sympathotonus and, peripherally, enhancement of the release and effects of norepinephrine. ACE inhibitors, such as captopril and enalaprilat, the active metabolite of enalapril, occupy the enzyme as false substrates.

 

In addition, a carrier (antiporter), utilizing the transmembrane Na+ gradient as energy source, transports Ca2+ out of the cell in exchange for Na+ moving down its transmembrane gradient (Na+/Ca2+ exchange).
In many cases, isolated organs or organ parts can be kept viable for hours in an appropriate nutrient medium sufficiently supplied with oxygen and held at a suitable temperature. Responses of the preparation to a physiological or pharmacological stimulus can be determined by a suitable recording apparatus.

 

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